PTFE Tubing: The Ultimate Guide to Chemical-Resistant, High-Purity Fluid Transfer | Polypac

Friday, December 12, 2025
Explore Polypac’s guide to PTFE tubing, featuring chemical-resistant, high-purity Teflon and reinforced PTFE tubing solutions for safe, reliable fluid transfer in demanding industrial applications. Discover expert insights and benefits tailored to your needs.

PTFE Tubing: The Unrivaled Solution for Demanding Fluid Transfer Applications

In industries where fluid transfer cannot compromise on purity, chemical resistance, or thermal stability, standard polymer or metal tubing often falls short. PTFE Tubing—manufactured from Polytetrafluoroethylene (commonly known as Teflon®)—stands as the premier material for handling the world's most aggressive chemicals, high-purity media, and extreme temperatures. More than just a hose, it is an engineered component critical to process integrity, safety, and reliability in some of the most technologically advanced sectors.

At Polypac, with our expertise in high-performance polymer solutions for special working conditions, we provide PTFE Tubing that meets the stringent demands of critical fluid handling systems. This guide explores the exceptional properties of PTFE tubing and its vital role across diverse industries.

What is PTFE Tubing?

PTFE Tubing is a flexible or semi-flexible conduit manufactured from extruded Polytetrafluoroethylene. Its unique molecular structure—a carbon backbone fully saturated with fluorine atoms—grants it a set of properties that no other common tubing material can match in totality.

This tubing is engineered for applications where failure is not an option, serving as the safe passage for:

  1. Ultra-Aggressive Chemicals: Acids, bases, solvents, and oxidizing agents.

  2. High-Purity & Sensitive Media: Pharmaceutical ingredients, semiconductor etchants, and high-purity water.

  3. High-Temperature Fluids & Gases: Steam, hot oils, and corrosive process streams at elevated temperatures.

Unmatched Properties of PTFE Tubing

PTFE's properties make it an indispensable material for critical fluid transfer:

1. Universal Chemical Resistance

PTFE is virtually inert, resistant to attack from almost all industrial chemicals. This includes:

  • Strong mineral acids (sulfuric, nitric, hydrochloric, hydrofluoric)

  • Caustic solutions and strong bases

  • Halogens and aggressive organic solvents

  • This makes it the default "safe choice" for unknown or mixed chemical streams.

2. Extraordinary Temperature Range

PTFE tubing maintains functionality across an exceptionally wide temperature spectrum:

  • Operating Range: -200°C to +260°C (-328°F to +500°F)

  • This eliminates the need for different tubing materials for hot and cold services, simplifying system design and inventory.

3. Excellent Dielectric Properties & Non-Stick Surface

  • Serves as an effective electrical insulator.

  • The inherent non-stick, low-friction surface minimizes pressure drop, prevents clogging, and allows for easy cleaning and complete draining.

4. High Purity and Biocompatibility

  • FDA Compliant and suitable for USP Class VI applications.

  • Does not leach contaminants, supports microbial growth, or impart taste or odor.

  • Ideal for sanitary, pharmaceutical, and food processing applications.

5. Flexibility & Durability

  • Maintains flexibility across its temperature range.

  • Resists aging, weathering, and UV degradation.

Key Applications of PTFE Tubing

PTFE Tubing is the material of choice in industries where process integrity is paramount:

  • Chemical Processing: Transfer lines for corrosive raw materials, intermediates, and finished products. Ideal for sampling lines and instrument air lines in corrosive atmospheres.

  • Pharmaceutical & Biotechnology: Fluid paths in bioreactors, chromatography systems, fermenters, and for conveying sensitive active pharmaceutical ingredients (APIs). Its cleanability is essential for Sterilize-in-Place (SIP) and Clean-in-Place (CIP) systems.

  • Semiconductor Manufacturing: Ultra-high-purity (UHP) gas and chemical delivery lines for wafer fabrication. Used for DI water, acids, solvents, and specialty gases where particle generation or metallic contamination is catastrophic.

  • Food & Beverage: Sanitary tubing for flavors, colors, acids (like citric acid), and aggressive cleaning solutions.

  • Analytical & Laboratory Equipment: Used in HPLC, ICP-MS, and other instrumentation where inert, contaminant-free fluid paths are critical for accurate results.

  • Aerospace & Automotive: For fuel, lubrication, and hydraulic lines in demanding environments.

Types and Forms of PTFE Tubing

PTFE tubing is available in various forms to suit specific needs:

  • Virgin PTFE Tubing: Offers the highest level of purity and chemical resistance.

  • Reinforced PTFE Tubing: Braided with stainless steel or other high-strength fibers to increase pressure ratings and burst strength while maintaining flexibility.

  • Heat-Shrinkable PTFE Tubing: Used for insulating and protecting wires, components, and fittings in harsh chemical or thermal environments.

  • Multi-Lumen PTFE Tubing: Contains multiple, separate channels within a single tube for compact, organized fluid or gas transfer.

The Polypac Advantage: Quality and Precision in Every Meter

We understand that the quality of tubing directly impacts system reliability. Our commitment ensures:

  • Material Integrity: We source high-grade, consistent PTFE resins to ensure batch-to-batch uniformity in properties and performance.

  • Precision Extrusion: Our tubing is manufactured to tight dimensional tolerances (ID, OD, wall thickness), ensuring consistent flow characteristics and reliable fitting connections.

  • Cleanliness & Certification: Tubing for critical industries is produced and handled in controlled environments and can be provided with relevant certifications (e.g., material certifications, FDA statements).

  • Technical Support: Our team can assist with selection based on chemical compatibility, pressure/temperature requirements, and connection type (e.g., flared, compression fittings).

Important Considerations

  • Gas Permeability: While excellent for liquids, PTFE can be permeable to certain gases and small molecule solvents over time. For critical gas applications, this must be evaluated.

  • Mechanical Strength: Virgin PTFE is relatively soft. For higher pressure applications or where abrasion is a concern, reinforced or thicker-walled options should be selected.

  • Installation: Proper techniques with appropriate fittings (often designed for PTFE) are crucial to prevent leaks, especially in high-purity or high-pressure systems.

Conclusion

PTFE Tubing is more than just a piece of plastic hose; it is a high-performance engineered component that enables innovation and ensures safety in the most demanding industrial processes. Its combination of chemical inertness, thermal stability, and purity is unmatched, making it an essential investment for any application where fluid integrity cannot be compromised.

When standard tubing materials present a risk of contamination, corrosion, or failure, PTFE provides a reliable and long-lasting solution.

Transferring aggressive chemicals, high-purity fluids, or operating in extreme temperatures? Trust the proven performance of PTFE. Contact Polypac's specialists today to select the perfect PTFE tubing specification for your critical application.

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FAQ
Products
How do I choose the right material for my sealing application?
Material selection depends on four key factors: Media: What fluid or gas will the seal contact? (e.g., petroleum oil, water, chemicals, steam) Temperature: What is the minimum and maximum operating temperature? Pressure: What is the system's operating pressure? Are there pressure spikes? Application: Is it a static, dynamic, or rotary seal? Example: NBR (Buna-N) is excellent for standard hydraulic oil, while FKM (Viton®) is needed for high temperatures or aggressive chemicals.
Why did my O-ring fail prematurely?
Common causes of O-ring failure include: Chemical Incompatibility: Swelling, softening, or cracking due to fluid exposure. Improper Sizing: Using an incorrect size leads to over-compression or inadequate sealing force. Abrasion: Wear and tear from rough surface finishes or contaminated fluid. Extrusion: The seal is forced into the gap between metal parts under high pressure. Installation Damage: Nicks, cuts, or twists during assembly.
Can I reuse a seal?
We strongly recommend never reusing seals. Once compressed and used, a seal takes a "set" and its elastic properties are degraded. Reusing it almost always results in a leak. Always install a new seal during any maintenance or repair.
What is the purpose of the metal spring in a rotary shaft seal?
The garter spring in a shaft seal (e.g., FSKR, SPGO types) provides a constant radial force on the sealing lip. This ensures consistent contact with the rotating shaft, compensating for minor wear, eccentricity, and vibration to prevent lubricant leakage.
What does "AS568" mean?
AS568 is the Aerospace Standard that defines the dimensions for over 360 standard O-ring sizes. It is the most widely accepted sizing system in North America and globally. An AS568 number (e.g., AS568-214) specifies a precise inside diameter and cross-section.
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